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Holding(s) in Company - 24 April 2008

24 April 2008

TR-1:               Notification of major interests in shares

1. Identity of the issuer or the underlying issuer of existing shares to System C Healthcare PLC which voting rights are attached:

2. Reason for the notification     (please tick the appropriate box or boxes)

An acquisition or disposal of voting rights                                              X

An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached

An event changing the breakdown of voting rights
Other (please specify):

3. Full name of person(s) subject to the notification obligation: AXA S.A. and its group of Companies

4. Full name of shareholder(s) (if different from 3.):

5. Date of the transaction (and date on which the threshold is crossed 22nd April 2008 or reached if different):

6. Date on which issuer notified:23rd April 2008

7. Threshold(s) that is/are crossed or reached:

8. Notified details:

A: Voting rights attached to shares
Class/type of       Situation previous to the    Resulting situation after the triggering transaction
shares              Triggering transaction
                    Number of       Number of    Number of     Number of voting rights   % of voting rights
if possible using  Shares          Voting       shares
the ISIN CODE                       Rights                     Direct       Indirect     Direct    Indirect

GB00B0940H91        5,757,635       5,757,635    6,282,635     650,000      5,632,635    0.73%     6.29%


B: Financial Instruments
Resulting situation after the triggering transaction
Type of financial    Expiration date Exercise/ Conversion      Number of voting rights    % of voting
instrument                           Period/ Date              that may be acquired if    rights
                                                               the instrument is
                                                               exercised/ converted.



Total (A+B)

Number of voting rights                            % of voting rights

6,282,635                                          7.02%

9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively
held, if applicable:
       Name of Company/Fund                  Number of Shares                % of issued share capital

Sun life Pensions Management Ltd                  125,000                             0.13959

Direct
Sun life Pensions Management Ltd                  525,000                             0.58627

Direct
AXA Framlington                                   500,000                             0.55836

SEI UK Equity

Indirect
AXA Framlington                                  2,562,753                            2.86186

Throgmorton Trust

Indirect
AXA Framlington                                   648,149                             0.72380

Framlington AIM VCT

Indirect
AXA Framlington                                  1,921,733                            2.14603

UK Smaller Companies

Indirect
                       Total Direct               650,000                             0.72586

                     Total Indirect              5,632,635                            6.29004

Proxy Voting:

10. Name of the proxy holder:

11. Number of voting rights proxy holder will cease to hold:

12. Date on which proxy holder will cease to hold voting rights:

13. Additional information:

14. Contact name:                               Jane Conner

15. Contact telephone number:                   01622 691616
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System C works within the English National Programme for IT in 4 out of the 5 regional clusters